Longevity & Aging
This focus area supports Longevity & Aging goals by highlighting nutrition, lifestyle, and supplement strategies that may help.
Explore the core themes below and review related supplements for deeper guidance.
Key themes
- Oxidative stress defense
- Cellular repair and recovery
- Healthy aging habits
How supplements fit in
Supplements are one part of the plan. Review the list below and check evidence, dosing, and safety notes.
Alpha-lipoic acid
Alpha-lipoic acid is a powerful antioxidant that is both water- and fat-soluble, allowing it to work throughout the body. It is approved in Germany for diabetic neuropathy treatment.
Key focuses:
Antioxidant Support
Metabolic Health
Cognitive Function
Bacopa monnieri
Bacopa monnieri, also known as Brahmi, is a traditional Ayurvedic herb renowned for its cognitive-enhancing and memory-supporting properties. It is one of the most studied nootropic herbs.
Key focuses:
Cognitive Function
Longevity & Aging
Stress & Sleep
Berberine
Berberine is a bioactive plant alkaloid with potent metabolic effects. Clinical studies demonstrate its ability to reduce blood glucose, improve insulin sensitivity, and lower cholesterol through AMPK activation, often called "natural metformin."
Key focuses:
Metabolic Health
Cardiovascular Health
Inflammation Response Support
Calcium
Calcium is an essential mineral required for strong bones and teeth, muscle contraction, nerve signaling, and blood clotting. It is obtained through dietary sources and supplements, and adequate intake is vital for skeletal integrity throughout life.
Key focuses:
Joint & Bone Health
Athletic SupportLongevity & Aging
Collagen
Collagen is the most abundant protein in the human body, providing structural support to skin, bones, tendons, and cartilage. Supplementation may improve skin hydration, elasticity, and joint comfort.
Key focuses:
Skin, Hair & NailsJoint & Bone HealthLongevity & Aging
Creatine
Creatine is a naturally occurring compound that plays a critical role in energy production, particularly during high-intensity, short-duration exercise. It is one of the most effective and well-researched supplements for increasing muscle strength, power, and lean body mass. Emerging research also suggests benefits for cognitive function.
Key focuses:
Athletic Support
Energy & VitalityCognitive Function
Fisetin
Fisetin is a natural flavonoid found in strawberries that acts as a senolytic - selectively removing aging "zombie" cells. It shows promise for healthy aging and longevity.
Key focuses:
Longevity & AgingCognitive FunctionAntioxidant Support
Glucosamine
Glucosamine is a natural compound found in cartilage and is a building block for glycosaminoglycans. It is widely used for osteoarthritis and joint health, though clinical evidence is mixed.
Key focuses:
Joint & Bone HealthLongevity & AgingCardiovascular Health
Hyaluronic Acid
Hyaluronic acid is a naturally occurring glycosaminoglycan that provides lubrication and cushioning in joints and hydration in skin. Oral supplementation shows promise for joint health and skin moisture, though bioavailability is limited compared to injectable forms.
Key focuses:
Joint & Bone HealthSkin, Hair & NailsInflammation Response Support
Lion's Mane Mushroom
Lion's Mane is a medicinal mushroom with neuroprotective properties. It contains unique compounds (hericenones and erinacines) that stimulate nerve growth factor (NGF) synthesis, supporting brain health, cognitive function, and nerve regeneration.
Key focuses:
Cognitive FunctionLongevity & Aging
Mood Support
Melatonin
Melatonin is a hormone produced by the pineal gland that regulates sleep-wake cycles. As a supplement, it is effective for jet lag, shift work sleep disorder, and insomnia in older adults. It is one of the safest sleep aids available with minimal side effects and no dependency risk.
Key focuses:
Stress & SleepAntioxidant Support
Immunity Support
NMN
NMN is a direct precursor to NAD+, a critical coenzyme for cellular energy metabolism and DNA repair. Declining NAD+ levels with age have sparked interest in NMN as a potential longevity supplement.
Key focuses:
Longevity & AgingEnergy & VitalityMetabolic Health